PEX11B

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Peroxisomal biogenesis factor 11 beta
Identifiers
Symbols PEX11B ; PEX11-BETA; PEX14B
External IDs OMIM603867 MGI1338882 HomoloGene2852 GeneCards: PEX11B Gene
RNA expression pattern
PBB GE PEX11B 202658 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8799 18632
Ensembl ENSG00000131779 ENSMUSG00000028102
UniProt O96011 Q9Z210
RefSeq (mRNA) NM_001184795 NM_001162387
RefSeq (protein) NP_001171724 NP_001155859
Location (UCSC) Chr 1:
145.52 – 145.52 Mb
Chr 3:
96.64 – 96.65 Mb
PubMed search [1] [2]

Peroxisomal membrane protein 11B is a protein that in humans is encoded by the PEX11B gene.[1][2] It is involved in the regulation of peroxisome abundance. [3]


Interactions[edit]

PEX11B has been shown to interact with PEX19.[4][5]

Related gene problems[edit]

References[edit]

  1. ^ Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (December 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem 273 (45): 29607–14. doi:10.1074/jbc.273.45.29607. PMID 9792670. 
  2. ^ "Entrez Gene: PEX11B peroxisomal biogenesis factor 11B". 
  3. ^ Thoms S, Erdmann R (October 2005). "Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation.". FEBS J 272 (20): 5169–81. doi:10.1111/j.1742-4658.2005.04939.x. PMID 16218949. 
  4. ^ Sacksteder, K A; Jones J M; South S T; Li X; Liu Y; Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. (UNITED STATES) 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547. PMID 10704444. 
  5. ^ Fransen, M; Wylin T; Brees C; Mannaerts G P; Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. (United States) 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101. PMID 11390669. 
  6. ^ Klopocki E, Schulze H, Strauss G, et al. (February 2007). "Complex Inheritance Pattern Resembling Autosomal Recessive Inheritance Involving a Microdeletion in Thrombocytopenia–Absent Radius Syndrome". Am. J. Hum. Genet. 80 (2): 232–40. doi:10.1086/510919. PMC 1785342. PMID 17236129. 

Further reading[edit]