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Peroxisomal biogenesis factor 11 beta
Symbols PEX11B ; PEX11-BETA; PEX14B
External IDs OMIM603867 MGI1338882 HomoloGene2852 GeneCards: PEX11B Gene
RNA expression pattern
PBB GE PEX11B 202658 at tn.png
More reference expression data
Species Human Mouse
Entrez 8799 18632
Ensembl ENSG00000131779 ENSMUSG00000028102
UniProt O96011 Q9Z210
RefSeq (mRNA) NM_001184795 NM_001162387
RefSeq (protein) NP_001171724 NP_001155859
Location (UCSC) Chr 1:
145.52 – 145.52 Mb
Chr 3:
96.64 – 96.65 Mb
PubMed search [1] [2]

Peroxisomal membrane protein 11B is a protein that in humans is encoded by the PEX11B gene.[1][2] It is involved in the regulation of peroxisome abundance. [3]


PEX11B has been shown to interact with PEX19.[4][5]

Related gene problems[edit]


  1. ^ Schrader M, Reuber BE, Morrell JC, Jimenez-Sanchez G, Obie C, Stroh TA, Valle D, Schroer TA, Gould SJ (December 1998). "Expression of PEX11beta mediates peroxisome proliferation in the absence of extracellular stimuli". J Biol Chem 273 (45): 29607–14. doi:10.1074/jbc.273.45.29607. PMID 9792670. 
  2. ^ "Entrez Gene: PEX11B peroxisomal biogenesis factor 11B". 
  3. ^ Thoms S, Erdmann R (October 2005). "Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation.". FEBS J 272 (20): 5169–81. doi:10.1111/j.1742-4658.2005.04939.x. PMID 16218949. 
  4. ^ Sacksteder, K A; Jones J M; South S T; Li X; Liu Y; Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. (UNITED STATES) 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547. PMID 10704444. 
  5. ^ Fransen, M; Wylin T; Brees C; Mannaerts G P; Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. (United States) 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101. PMID 11390669. 
  6. ^ Klopocki E, Schulze H, Strauss G et al. (February 2007). "Complex Inheritance Pattern Resembling Autosomal Recessive Inheritance Involving a Microdeletion in Thrombocytopenia–Absent Radius Syndrome". Am. J. Hum. Genet. 80 (2): 232–40. doi:10.1086/510919. PMC 1785342. PMID 17236129. 

Further reading[edit]