PEX13

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Peroxisomal biogenesis factor 13
Protein PEX13 PDB 1wxu.png
PDB rendering based on 1wxu.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols PEX13 ; NALD; PBD11A; PBD11B; ZWS
External IDs OMIM601789 MGI1919379 HomoloGene1967 GeneCards: PEX13 Gene
RNA expression pattern
PBB GE PEX13 205246 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5194 72129
Ensembl ENSG00000162928 ENSMUSG00000020283
UniProt Q92968 Q9D0K1
RefSeq (mRNA) NM_002618 NM_023651
RefSeq (protein) NP_002609 NP_076140
Location (UCSC) Chr 2:
61.24 – 61.28 Mb
Chr 11:
23.65 – 23.67 Mb
PubMed search [1] [2]

Peroxisomal membrane protein PEX13 is a protein that in humans is encoded by the PEX13 gene.[1][2] It located on chromosome 2 next to KIAA1841

Interactions[edit]

PEX13 has been shown to interact with PEX14,[3] PEX5[3][4] and PEX19.[5][6]

References[edit]

  1. ^ Bjorkman J, Stetten G, Moore CS, Gould SJ, Crane DI (February 1999). "Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene". Genomics 54 (3): 521–8. doi:10.1006/geno.1998.5520. PMID 9878256. 
  2. ^ "Entrez Gene: PEX13 peroxisome biogenesis factor 13". 
  3. ^ a b Otera, Hidenori; Setoguchi Kiyoko, Hamasaki Maho, Kumashiro Toshitaka, Shimizu Nobuhiro, Fujiki Yukio (March 2002). "Peroxisomal Targeting Signal Receptor Pex5p Interacts with Cargoes and Import Machinery Components in a Spatiotemporally Differentiated Manner: Conserved Pex5p WXXXF/Y Motifs Are Critical for Matrix Protein Import". Mol. Cell. Biol. (United States) 22 (6): 1639–55. doi:10.1128/MCB.22.6.1639-1655.2002. ISSN 0270-7306. PMC 135613. PMID 11865044. 
  4. ^ Gould, S J; Kalish J E, Morrell J C, Bjorkman J, Urquhart A J, Crane D I (October 1996). "Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTs1 receptor". J. Cell Biol. (UNITED STATES) 135 (1): 85–95. doi:10.1083/jcb.135.1.85. ISSN 0021-9525. PMC 2121023. PMID 8858165. 
  5. ^ Sacksteder, K A; Jones J M, South S T, Li X, Liu Y, Gould S J (March 2000). "Pex19 Binds Multiple Peroxisomal Membrane Proteins, Is Predominantly Cytoplasmic, and Is Required for Peroxisome Membrane Synthesis". J. Cell Biol. (UNITED STATES) 148 (5): 931–44. doi:10.1083/jcb.148.5.931. ISSN 0021-9525. PMC 2174547. PMID 10704444. 
  6. ^ Fransen, M; Wylin T, Brees C, Mannaerts G P, Van Veldhoven P P (July 2001). "Human Pex19p Binds Peroxisomal Integral Membrane Proteins at Regions Distinct from Their Sorting Sequences". Mol. Cell. Biol. (United States) 21 (13): 4413–24. doi:10.1128/MCB.21.13.4413-4424.2001. ISSN 0270-7306. PMC 87101. PMID 11390669. 

Further reading[edit]

External links[edit]