Pirin Gotse Delchev were founded in 1925 as Pirin Nevrokop (Nevrokop being the former name of Gotse Delchev), and their traditional colours are green and white. In 1981–82 Pirin were promoted for the first time to B PFG. The club spent three years in second division, before being relegated in 1985 to third division.
After 8 years in the lowers divisions of Bulgarian football, in 1993 Pirin returned to B PFG. In their first season back in second division Pirin finished in eight place in the league. In the following 1994–95 season was a poor one for the club, ending with the team in second lowest place and relegated back to the third division.
In 2005 they won the third promotion to the B PFG in its history. In December 2005, Yordan Bozdanski was appointed as manager. Pirin finished the 2006–07 season in third place in the West B PFG, their highest finish in the league since their еstablishment.
On 27 June 2011, Yakov Paparkov was officially announced as the club's new manager. In the 2011–12 season, Pirin won the West B PFG with a 62 points, scoring 41 goals and losing only three times. Pirin were promoted to Bulgarian football's top division for the first time in their history.