PICO process

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The PICO process (an acronym for patient problem or population (P), intervention (I), comparison (C) and outcome(s) (O).[1]) (the terms Control or Comparator for "C" are also used.[2]) is a technique used in evidence based practice to frame and answer a clinical question.[3][4][5]


  1. ^ "PICO". Retrieved 2010-05-18. 
  2. ^ "Chapter 2. Systematic Review Methods -- AHRQ Technical Reviews and Summaries -- NCBI Bookshelf". Retrieved 2010-05-18. 
  3. ^ "EBM - Question Formulation". Retrieved 2010-05-18. 
  4. ^ Huang X, Lin J, Demner-Fushman D (2006). "Evaluation of PICO as a knowledge representation for clinical questions". AMIA Annu Symp Proc: 359–63. PMC 1839740. PMID 17238363. 
  5. ^ Schardt C, Adams MB, Owens T, Keitz S, Fontelo P (2007). "Utilization of the PICO framework to improve searching PubMed for clinical questions". BMC Med Inform Decis Mak 7: 16. doi:10.1186/1472-6947-7-16. PMC 1904193. PMID 17573961.