PLEK2

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Pleckstrin 2
Protein PLEK2 PDB 1v3f.png
PDB rendering based on 1v3f.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbol PLEK2
External IDs OMIM608007 MGI1351466 HomoloGene8447 GeneCards: PLEK2 Gene
RNA expression pattern
PBB GE PLEK2 218644 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 26499 27260
Ensembl ENSG00000100558 ENSMUSG00000021118
UniProt Q9NYT0 Q9WV52
RefSeq (mRNA) NM_016445 NM_013738
RefSeq (protein) NP_057529 NP_038766
Location (UCSC) Chr 14:
67.85 – 67.88 Mb
Chr 12:
78.89 – 78.91 Mb
PubMed search [1] [2]

Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene.[1][2][3] The PLEK2 gene is located on chromosome 14 in Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.[4]


References[edit]

  1. ^ Lemmon MA, Ferguson KM, Abrams CS (Mar 2002). "Pleckstrin homology domains and the cytoskeleton". FEBS Lett 513 (1): 71–6. doi:10.1016/S0014-5793(01)03243-4. PMID 11911883. 
  2. ^ Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y (Aug 2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading". Biochem Biophys Res Commun 361 (2): 270–5. doi:10.1016/j.bbrc.2007.06.132. PMID 17658464. 
  3. ^ "Entrez Gene: PLEK2 pleckstrin 2". 
  4. ^ "AceView: PLEK2 gene". AceView. National Library of Medicine. Retrieved 24 April 2011. 

Further reading[edit]