PLRG1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Pleiotropic regulator 1
Identifiers
Symbols PLRG1 ; Cwc1; PRL1; PRP46; PRPF46; TANGO4
External IDs OMIM605961 MGI1858197 HomoloGene2004 GeneCards: PLRG1 Gene
Orthologs
Species Human Mouse
Entrez 5356 53317
Ensembl ENSG00000171566 ENSMUSG00000027998
UniProt O43660 Q922V4
RefSeq (mRNA) NM_001201564 NM_016784
RefSeq (protein) NP_001188493 NP_058064
Location (UCSC) Chr 4:
155.46 – 155.47 Mb
Chr 3:
83.06 – 83.07 Mb
PubMed search [1] [2]

Pleiotropic regulator 1 is a protein that in humans is encoded by the PLRG1 gene.[1]


Interactions[edit]

PLRG1 has been shown to interact with CDC5L.[2][3][4][5]

References[edit]

  1. ^ "Entrez Gene: PLRG1 pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)". 
  2. ^ Ewing, Rob M; Chu Peter, Elisma Fred, Li Hongyan, Taylor Paul, Climie Shane, McBroom-Cerajewski Linda, Robinson Mark D, O'Connor Liam, Li Michael, Taylor Rod, Dharsee Moyez, Ho Yuen, Heilbut Adrian, Moore Lynda, Zhang Shudong, Ornatsky Olga, Bukhman Yury V, Ethier Martin, Sheng Yinglun, Vasilescu Julian, Abu-Farha Mohamed, Lambert Jean-Philippe, Duewel Henry S, Stewart Ian I, Kuehl Bonnie, Hogue Kelly, Colwill Karen, Gladwish Katharine, Muskat Brenda, Kinach Robert, Adams Sally-Lin, Moran Michael F, Morin Gregg B, Topaloglou Thodoros, Figeys Daniel (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. (England) 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. 
  3. ^ Ajuh, Paul; Lamond Angus I (November 2003). "Identification of peptide inhibitors of pre-mRNA splicing derived from the essential interaction domains of CDC5L and PLRG1". Nucleic Acids Res. (England) 31 (21): 6104–16. doi:10.1093/nar/gkg817. PMC 275459. PMID 14576297. 
  4. ^ Ajuh, P; Sleeman J; Chusainow J; Lamond A I (November 2001). "A direct interaction between the carboxyl-terminal region of CDC5L and the WD40 domain of PLRG1 is essential for pre-mRNA splicing". J. Biol. Chem. (United States) 276 (45): 42370–81. doi:10.1074/jbc.M105453200. ISSN 0021-9258. PMID 11544257. 
  5. ^ Ajuh, P; Kuster B; Panov K; Zomerdijk J C; Mann M; Lamond A I (December 2000). "Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry". EMBO J. (ENGLAND) 19 (23): 6569–81. doi:10.1093/emboj/19.23.6569. ISSN 0261-4189. PMC 305846. PMID 11101529. 

Further reading[edit]