POLK

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Polymerase (DNA directed) kappa
Protein POLK PDB 1t94.png
PDB rendering based on 1t94.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols POLK ; DINB1; DINP; POLQ
External IDs OMIM605650 MGI1349767 HomoloGene32140 ChEMBL: 5365 GeneCards: POLK Gene
EC number 2.7.7.7
Orthologs
Species Human Mouse
Entrez 51426 27015
Ensembl ENSG00000122008 ENSMUSG00000021668
UniProt Q9UBT6 Q9QUG2
RefSeq (mRNA) NM_016218 NM_012048
RefSeq (protein) NP_057302 NP_036178
Location (UCSC) Chr 5:
75.51 – 75.6 Mb
Chr 13:
96.48 – 96.54 Mb
PubMed search [1] [2]

DNA polymerase kappa is an enzyme that in humans is encoded by the POLK gene.[1][2][3]


References[edit]

  1. ^ Ohashi E, Ogi T, Kusumoto R, Iwai S, Masutani C, Hanaoka F, Ohmori H (Aug 2000). "Error-prone bypass of certain DNA lesions by the human DNA polymerase κ". Genes Dev 14 (13): 1589–94. PMC 316741. PMID 10887153. 
  2. ^ Gerlach VL, Aravind L, Gotway G, Schultz RA, Koonin EV, Friedberg EC (Nov 1999). "Human and mouse homologs of Escherichia coli DinB (DNA polymerase IV), members of the UmuC/DinB superfamily". Proc Natl Acad Sci U S A 96 (21): 11922–7. doi:10.1073/pnas.96.21.11922. PMC 18388. PMID 10518552. 
  3. ^ "Entrez Gene: POLK Polymerase (DNA directed) kappa". 

Further reading[edit]