POMT2

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Protein-O-mannosyltransferase 2
Identifiers
Symbols POMT2 ; LGMD2N; MDDGA2; MDDGB2; MDDGC2
External IDs OMIM607439 MGI2444430 HomoloGene5297 GeneCards: POMT2 Gene
EC number 2.4.1.109
RNA expression pattern
PBB GE POMT2 220632 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 29954 217734
Ensembl ENSG00000009830 ENSMUSG00000034126
UniProt Q9UKY4 Q8BGQ4
RefSeq (mRNA) NM_013382 NM_153415
RefSeq (protein) NP_037514 NP_700464
Location (UCSC) Chr 14:
77.74 – 77.79 Mb
Chr 12:
87.11 – 87.15 Mb
PubMed search [1] [2]

Protein O-mannosyl-transferase 2 is an enzyme that in humans is encoded by the POMT2 gene.[1][2][3]

Function[edit]

POMT2 encodes an integral membrane protein of the endoplasmic reticulum (ER) that shares significant sequence similarity with a family of protein O-mannosyltransferases of S. cerevisiae. For additional background information, see POMT1 (MIM 607423).[supplied by OMIM][3]

References[edit]

  1. ^ Fukuda S, Sumii M, Masuda Y, Takahashi M, Koike N, Teishima J, Yasumoto H, Itamoto T, Asahara T, Dohi K, Kamiya K (Feb 2001). "Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family". Biochem Biophys Res Commun 280 (1): 407–14. doi:10.1006/bbrc.2000.4111. PMID 11162531. 
  2. ^ Willer T, Amselgruber W, Deutzmann R, Strahl S (Dec 2002). "Characterization of POMT2, a novel member of the PMT protein O-mannosyltransferase family specifically localized to the acrosome of mammalian spermatids". Glycobiology 12 (11): 771–83. doi:10.1093/glycob/cwf086. PMID 12460945. 
  3. ^ a b "Entrez Gene: POMT2 protein-O-mannosyltransferase 2". 

Further reading[edit]

External links[edit]