POU4F2

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POU class 4 homeobox 2
Identifiers
Symbols POU4F2 ; BRN3.2; BRN3B; Brn-3b
External IDs OMIM113725 MGI102524 HomoloGene20959 GeneCards: POU4F2 Gene
RNA expression pattern
PBB GE POU4F2 207725 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5458 18997
Ensembl ENSG00000151615 ENSMUSG00000031688
UniProt Q12837 Q63934
RefSeq (mRNA) NM_004575 NM_138944
RefSeq (protein) NP_004566 NP_620394
Location (UCSC) Chr 4:
147.56 – 147.56 Mb
Chr 8:
78.43 – 78.44 Mb
PubMed search [1] [2]

POU domain, class 4, transcription factor 2 is a protein that in humans is encoded by the POU4F2 gene.[1][2]

POU4F2 is a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F2 is found in human retina exclusively within a subpopulation of ganglion cells where it may play a role in determining or maintaining the identities of a small subset of visual system neurons.[supplied by OMIM][2]

Interactions[edit]

POU4F2 has been shown to interact with Estrogen receptor alpha.[3]

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.