PPFIA4

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Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
Identifiers
Symbol PPFIA4
External IDs OMIM603145 MGI1915757 HomoloGene66200 GeneCards: PPFIA4 Gene
RNA expression pattern
PBB GE PPFIA4 214978 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8497 68507
Ensembl ENSG00000143847 ENSMUSG00000026458
UniProt O75335 B8QI36
RefSeq (mRNA) NM_015053 NM_001144855.1
RefSeq (protein) NP_055868 NP_001138327.1
Location (UCSC) Chr 1:
203 – 203.05 Mb
Chr 1:
136.19 – 136.23 Mb
PubMed search [1] [2]

Liprin-alpha-4 is a protein that in humans is encoded by the PPFIA4 gene.[1][2]

Interactions[edit]

PPFIA4 has been shown to interact with:

References[edit]

  1. ^ Serra-Pagès C, Medley QG, Tang M, Hart A, Streuli M (Jul 1998). "Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins". J Biol Chem 273 (25): 15611–20. doi:10.1074/jbc.273.25.15611. PMID 9624153. 
  2. ^ "Entrez Gene: PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4". 
  3. ^ a b Ko J, Na M, Kim S, Lee JR, Kim E (Oct 2003). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177. 
  4. ^ Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M et al. (Mar 2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting". J. Neurosci. 23 (5): 1667–77. PMID 12629171. 
  5. ^ Wyszynski M, Kim E, Dunah AW, Passafaro M, Valtschanoff JG, Serra-Pagès C et al. (Mar 2002). "Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting". Neuron 34 (1): 39–52. doi:10.1016/s0896-6273(02)00640-2. PMID 11931740. 

Further reading[edit]

  • Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Millar JK, Christie S, Porteous DJ (2004). "Yeast two-hybrid screens implicate DISC1 in brain development and function.". Biochem. Biophys. Res. Commun. 311 (4): 1019–25. doi:10.1016/j.bbrc.2003.10.101. PMID 14623284. 
  • Katoh M, Katoh M (2004). "Identification and characterization of human PPFIA4 gene in silico.". Int. J. Mol. Med. 12 (6): 1009–14. doi:10.3892/ijmm.12.6.1009. PMID 14612982. 
  • Ko J, Na M, Kim S, Lee JR, Kim E (2004). "Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins.". J. Biol. Chem. 278 (43): 42377–85. doi:10.1074/jbc.M307561200. PMID 12923177. 
  • Ko J, Kim S, Valtschanoff JG, Shin H, Lee JR, Sheng M et al. (2003). "Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting.". J. Neurosci. 23 (5): 1667–77. PMID 12629171. 
  • Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355–64. doi:10.1093/dnares/5.6.355. PMID 10048485.