PRX (gene)

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Periaxin
Identifiers
Symbols PRX ; CMT4F
External IDs OMIM605725 MGI108176 HomoloGene76542 GeneCards: PRX Gene
RNA expression pattern
PBB GE PRX 220024 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 57716 19153
Ensembl ENSG00000105227 ENSMUSG00000053198
UniProt Q9BXM0 O55103
RefSeq (mRNA) NM_020956 NM_019412
RefSeq (protein) NP_066007 NP_062285
Location (UCSC) Chr 19:
40.9 – 40.92 Mb
Chr 7:
27.5 – 27.52 Mb
PubMed search [1] [2]

Periaxin is a protein that in humans is encoded by the PRX gene.[1][2][3]

The PRX gene encodes L- and S-periaxin, proteins of myelinating Schwann cells, and is mutated in Dejerine-Sottas syndrome (MIM 145900) and Charcot-Marie-Tooth disease type 4F (MIM 145900).[supplied by OMIM][3]

References[edit]

  1. ^ Gillespie CS, Sherman DL, Fleetwood-Walker SM, Cottrell DF, Tait S, Garry EM, Wallace VC, Ure J, Griffiths IR, Smith A, Brophy PJ (Jun 2000). "Peripheral demyelination and neuropathic pain behavior in periaxin-deficient mice". Neuron 26 (2): 523–31. doi:10.1016/S0896-6273(00)81184-8. PMID 10839370. 
  2. ^ Gillespie CS, Lee M, Fantes JF, Brophy PJ (Jul 1997). "The gene encoding the Schwann cell protein periaxin localizes on mouse chromosome 7 (Prx)". Genomics 41 (2): 297–8. doi:10.1006/geno.1997.4630. PMID 9143514. 
  3. ^ a b "Entrez Gene: PRX periaxin". 

Further reading[edit]

External links[edit]