PSCDBP

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Cytohesin 1 interacting protein
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols CYTIP ; B3-1; CASP; CYBR; CYTHIP; HE; PSCDBP
External IDs OMIM604448 MGI2183535 HomoloGene3167 GeneCards: CYTIP Gene
RNA expression pattern
PBB GE PSCDBP 209606 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 9595 227929
Ensembl ENSG00000115165 ENSMUSG00000026832
UniProt O60759 Q91VY6
RefSeq (mRNA) NM_004288 NM_139200
RefSeq (protein) NP_004279 NP_631939
Location (UCSC) Chr 2:
158.27 – 158.35 Mb
Chr 2:
58.13 – 58.2 Mb
PubMed search [1] [2]

Cytohesin-interacting protein is a protein that in humans is encoded by the CYTIP gene.[1][2][3][4]

The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, and it does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells.[4]

References[edit]

  1. ^ Dixon B, Sahely B, Liu L, Pohajdak B (Jan 1994). "Cloning a cDNA from human NK/T cells which codes for an unusual leucine zipper containing protein". Biochim Biophys Acta 1216 (2): 321–4. doi:10.1016/0167-4781(93)90165-a. PMID 8241278. 
  2. ^ Kim HS (Jun 1999). "Assignment of the human B3-1 gene (PSCDBP) to chromosome 2 band q11.2 by radiation hybrid mapping". Cytogenet Cell Genet 84 (1-2): 95. doi:10.1159/000015226. PMID 10343115. 
  3. ^ Tang P, Cheng TP, Agnello D, Wu CY, Hissong BD, Watford WT, Ahn HJ, Galon J, Moss J, Vaughan M, O'Shea JJ, Gadina M (Mar 2002). "Cybr, a cytokine-inducible protein that binds cytohesin-1 and regulates its activity". Proc Natl Acad Sci USA 99 (5): 2625–9. doi:10.1073/pnas.052712999. PMC 122398. PMID 11867758. 
  4. ^ a b "Entrez Gene: PSCDBP pleckstrin homology, Sec7 and coiled-coil domains, binding protein". 

Further reading[edit]