PSG1 (gene)

Pregnancy specific beta-1-glycoprotein 1
Identifiers
Symbols	PSG1; B1G1; CD66f; DHFRP2; FLJ90598; FLJ90654; PBG1; PSBG1; PSGGA; PSGIIA; SP1
External IDs	OMIM: 176390 GeneCards: PSG1 Gene
Gene Ontology Cellular component • extracellular region Biological process • female pregnancy Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	5669	n/a
Ensembl	ENSG00000231924	n/a
UniProt	P11464	n/a
RefSeq (mRNA)	NM_001184825.1	n/a
RefSeq (protein)	NP_001171754.1	n/a
Location (UCSC)	Chr 19: 43.34 – 43.38 Mb	n/a
PubMed search	[1]	n/a

Pregnancy specific beta-1-glycoprotein 1 (PSG1) also known as CD66f (Cluster of Differentiation 66f), is a human gene.

See also

• Cluster of differentiation

Further reading

• Khan WN, Teglund S, Bremer K, Hammarström S (1992). "The pregnancy-specific glycoprotein family of the immunoglobulin superfamily: identification of new members and estimation of family size". Genomics 12 (4): 780–787. doi:10.1016/0888-7543(92)90309-G. PMID 1572651. 
• Streydio C, Swillens S, Georges M et al (1990). "Structure, evolution and chromosomal localization of the human pregnancy-specific beta 1 glycoprotein gene family". Genomics 6 (4): 579–592. doi:10.1016/0888-7543(90)90492-D. PMID 2341148. 
• Zheng QX, Tease LA, Shupert WL, Chan WY (1990). "Characterization of cDNAs of the human pregnancy-specific beta 1-glycoprotein family, a new subfamily of the immunoglobulin gene superfamily". Biochemistry 29 (11): 2845–2852. doi:10.1021/bi00463a030. PMID 2346748. 
• Zoubir F, Khan WN, Hammarström S (1990). "Carcinoembryonic antigen gene family members in submandibular salivary gland: demonstration of pregnancy-specific glycoproteins by cDNA cloning". Biochem. Biophys. Res. Commun. 169 (1): 203–216. doi:10.1016/0006-291X(90)91455-2. PMID 2350345. 
• Leslie KK, Watanabe S, Lei KJ et al (1990). "Linkage of two human pregnancy-specific beta 1-glycoprotein genes: one is associated with hydatidiform mole". Proc. Natl. Acad. Sci. U.S.A. 87 (15): 5822–5826. doi:10.1073/pnas.87.15.5822. PMC 54420. PMID 2377620. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=54420. 
• Thompson JA, Mauch EM, Chen FS et al (1989). "Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons". Biochem. Biophys. Res. Commun. 158 (3): 996–1004. doi:10.1016/0006-291X(89)92821-0. PMID 2537643. 
• Khan WN, Osterman A, Hammarström S (1989). "Molecular cloning and expression of cDNA for a carcinoembryonic antigen-related fetal liver glycoprotein". Proc. Natl. Acad. Sci. U.S.A. 86 (9): 3332–3336. doi:10.1073/pnas.86.9.3332. PMC 287126. PMID 2541441. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=287126. 
• Khan WN, Hammarström S (1989). "Carcinoembryonic antigen gene family: molecular cloning of cDNA for a PS beta G/FL-NCA glycoprotein with a novel domain arrangement". Biochem. Biophys. Res. Commun. 161 (2): 525–535. doi:10.1016/0006-291X(89)92631-4. PMID 2735907. 
• Zimmermann W, Weiss M, Thompson JA (1989). "cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver". Biochem. Biophys. Res. Commun. 163 (3): 1197–1209. doi:10.1016/0006-291X(89)91105-4. PMID 2783133. 
• Niemann SC, Flake A, Bohn H, Bartels I (1989). "Pregnancy-specific beta 1-glycoprotein: cDNA cloning, tissue expression, and species specificity of one member of the PS beta G family". Hum. Genet. 82 (3): 239–243. doi:10.1007/BF00291162. PMID 2786492. 
• Chan WY, Borjigin J, Zheng QX, Shupert WL (1988). "Characterization of cDNA encoding human pregnancy-specific beta 1-glycoprotein from placenta and extraplacental tissues and their comparison with carcinoembryonic antigen". DNA 7 (8): 545–55. doi:10.1089/dna.1.1988.7.545. PMID 3180995. 
• Watanabe S, Chou JY (1988). "Isolation and characterization of complementary DNAs encoding human pregnancy-specific beta 1-glycoprotein". J. Biol. Chem. 263 (4): 2049–54. PMID 3257488. 
• Streydio C, Lacka K, Swillens S, Vassart G (1988). "The human pregnancy-specific beta 1-glycoprotein (PS beta G) and the carcinoembryonic antigen (CEA)-related proteins are members of the same multigene family". Biochem. Biophys. Res. Commun. 154 (1): 130–137. doi:10.1016/0006-291X(88)90660-2. PMID 3260773. 
• Rooney BC, Horne CH, Hardman N (1989). "Molecular cloning of a cDNA for human pregnancy-specific beta 1-glycoprotein:homology with human carcinoembryonic antigen and related proteins". Gene 71 (2): 439–449. doi:10.1016/0378-1119(88)90061-3. PMID 3265688. 
• Teglund S, Zhou GQ, Hammarström S (1995). "Characterization of cDNA encoding novel pregnancy-specific glycoprotein variants". Biochem. Biophys. Res. Commun. 211 (2): 656–664. doi:10.1006/bbrc.1995.1862. PMID 7794280. 
• Zhou GQ, Baranov V, Zimmermann W et al (1997). "Highly specific monoclonal antibody demonstrates that pregnancy-specific glycoprotein (PSG) is limited to syncytiotrophoblast in human early and term placenta". Placenta 18 (7): 491–501. doi:10.1016/0143-4004(77)90002-9. PMID 9290143. 
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–1795. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948. 
• Motrán CC, Díaz FL, Gruppi A et al (2002). "Human pregnancy-specific glycoprotein 1a (PSG1a) induces alternative activation in human and mouse monocytes and suppresses the accessory cell-dependent T cell proliferation". J. Leukoc. Biol. 72 (3): 512–21. PMID 12223519. 
• Strausberg RL, Feingold EA, Grouse LH et al (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T et al (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039. 

External links

• MeSH PSG1+protein,+human

This article incorporates text from the United States National Library of Medicine, which is in the public domain.