Pagodane

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Pagodane
Stereo, skeletal formula of pagodane
Ball and stick model of pagodane
Identifiers
89683-62-5 YesY
ChemSpider 128087 YesY
Jmol-3D images Image
PubChem 145202
Properties
C20H20
Molar mass 260.37 g·mol−1
Density 1.629 g/ml
Structure
Point group D2h
Dipole moment 0 D
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

Pagodane is an organic compound with formula C
20
H
20
whose carbon skeleton was said to resemble a pagoda, hence the name. It is a polycyclic hydrocarbon whose molecule has the D2h point symmetry group. The compound is a highly crystalline solid that melts at 243 °C, is barely soluble in most organic solvents and moderately soluble in benzene and chloroform. It sublimes at low pressure.[1]

The name pagodane is used more generally for any member of a family of compounds whose molecular skeletons have the same 16-carbon central cage as the basic compound. Each member can be seen as the result of connecting eight atoms of this cage in pairs by four alkane chains. The general member is denoted [m.n.p.q]pagodane where m, n, p and q are the number of carbons of those four chains. The general formula is then C
16+s
H
12+2s
where s= m+n+p+q. In particular, the basic compound C
20
H
20
has those carbons connected by four methylene bridges (m=n=p=q=1), and its name within that family is therefore [1.1.1.1]pagodane.[1]

Synthesis and structure[edit]

The compound was first synthesized by H. Prinzbach et al. in 1987, by a 14-step sequence starting from isodrin.[1] In the process they also synthesized [2.2.1.1]pagodane C
22
H
24
and several derivatives.

Prinzbach and co-workers remarked that "the obvious need for [the short name 'pagodane'] can be readily understood in view of the von Baeyer/IUPAC and Chemical Abstracts nomenclature", undecacyclo[9.9.0.01,5.02,12.02,18.03,7.06,10.08,12.011,15.013,17.316,20]icosane.[1]

Eight of pagodane's 20 carbon atoms (numbered 3,5,8,10,13,15,18, and 20) have an inverted tetrahedral geometry as in some propellanes – specifically, [2.2.1]propellane, whose carbon skeleton is a part of pagodane's.[1]

The overall synthesis can be summarized as follows: [1][2]

Synthesis of pagodane starting from isodrin

The scheme depicted here may be shortened to 14 one-pot operations with 24% overall yield. Yet, this variation requires the use of tetrachlorothiophenedioxide instead of tetrachloro-dimethoxycyclopentadiene in two of the early steps. While lesser steps and higher yield look attractive at first sight, this approach had to be given up due to high cost and restricted availability of the dioxide.[1]

Derivatives[edit]

Several derivatives are available, such as the diketone C
20
H
16
O
2
(melting point about 322 °C).[1]

Both [1.1.1.1]pagodane and [2.2.1.1]pagodane form divalent cations in SbF
5
/SO
2
ClF
. In these cations the electron deficiency is spread over the central cyclobutane ring.[3] These dications were the first examples to show the phenomenon of σ-bishomoaromaticity which was subsequently studied by the Prizbach group to great length.[4]

Pagodane is an isomer of dodecahedrane and can be chemically converted to it.[5][6]

References[edit]

  1. ^ a b c d e f g h Wolf-Dieter Fessner, Gottfried Sedelmeier, Paul R. Spurr, Grety Rihs, H. Prinzbach (1987), "Pagodane": the efficient synthesis of a novel, versatile molecular framework. J. Am. Chem. Soc., volume 109 issue 15, pp. 4626–42 doi:10.1021/ja00249a029
  2. ^ H. Prinzbach, F. Wahl, A. Weiler, P. Landenberger, J. Woerth, L.T. Scott, M. Gelmont, D. Olevano, F. Sommer, B. von Issendorff: C20 Carbon Clusters: Fullerene - Boat - Sheet Generation, Mass Selection, PE Characterization. Chem. Eur. J. 2006, 12, 6268-6280 | doi:10.1002/chem.200501611
  3. ^ G. K. Surya Prakash (1998), Investigations on intriguing long lived carbodications. Pure & Appl. Chem., volume 70 issue 10, pp. 2001–06. Online version at iupac.org accessed on 2010-01-14. doi:10.1351/pac199870102001
  4. ^ G.K.S. Prakash, V.V. Krishnamurthy, R. Herges, R. Bau, H. Yuan, G.A Olah, W.-D. Fessner, H. Prinzbach: [1.1.1.1]- and [2.2.1.1]Pagodane Dications: Frozen Two-Electron Woodward-Hoffmann Transition State Models. J. Am. Chem. Soc. 1988, 110, 7764-7772
  5. ^ Wolf-Dieter Fessner, Bulusu A. R. C. Murty, Horst Prinzbach (1987), The Pagodane Route to Dodecahedranes – Thermal, Reductive, and Oxidative Transformations of Pagodanes Angewandte Chemie International Edition in English Volume 26, Issue 5, pp. 451–52 doi:10.1002/anie.198704511
  6. ^ Wolf-Dieter Fessner, Bulusu A. R. C. Murty, Jürgen Wörth, Dieter Hunkler, Hans Fritz, Horst Prinzbach, Wolfgang D. Roth, Paul von Ragué Schleyer, Alan B. McEwen, Wilhelm F. Maier (1987), Dodecahedranes from [1.1.1.1]Pagodanes. Angewandte Chemie International Edition in English, Volume 26, Issue 5, pp. 452–54 doi:10.1002/anie.198704521