Panadol is the GlaxoSmithKline trade name for paracetamol (INN) (// or //) or acetaminophen (USAN) i//, which is an over the counter (OTC) pharmaceutical analgesic (pain reliever) and antipyretic (fever reducer). Paracetamol is most widely sold under this trade name in the United Kingdom, Australia, the Kingdom of Saudi Arabia, and New Zealand.
In 1955, Panadol was introduced to hospitals in the United Kingdom. It was first marketed by Phillips, Scott & Turner, which was acquired by Frederick Stearns & Co, a subsidiary of Sterling Drug Inc. It was advertised as being "gentle on the stomach", since other analgesic agents at the time contained aspirin, a known stomach irritant. Panadol was originally available only by prescription in the UK, but is now available over the counter. In 1988 Sterling Winthrop was acquired by Eastman Kodak which sold the over the counter drug rights to SmithKline Beecham in 1994.
Panadol is sold in different formulations and with different names, including:
- Panadol Extra
- Panadol Rapid
- Panadol Night
- Panadol Extra Strength (sold in Latin America-based countries)
- Panadol Multi-Symptom (sold in Latin America-based countries)
- Panadol Osteo
- Panadol Extend Tablets
Panadol Extra, an S2 pharmacy-only medicine in Australia, combines 65 mg of caffeine (65 mg) with 500 mg of paracetamol per tablet, which may improve the analgesic effect of paracetamol, though the extent of this effect “is uncertain and may not be clinically meaningful”, according to one review.
Panadol Osteo and Panadol Extend Tablets are modified-release formulations of paracetamol. Panadol Osteo is marketed in Australia and New Zealand; its immediate to sustained release ratio is 33% to 66%.
- GlaxoSmithKline | Panadol 50 Years
- SEC Info| Eastman Kodak Co | 8-K | For 6/30/94
- "Paracetamol with caffeine (Panadol Extra) available over the counter from pharmacies". NPS Radar. National Prescribing Service. Retrieved 10 August 2012.
- Graudins, A.; Chiew, A.; Chan, B. (2010). "Overdose with modified-release paracetamol results in delayed and prolonged absorption of paracetamol" (PDF). Internal Medicine Journal 40 (1): 72–76. doi:10.1111/j.1445-5994.2009.02096.x. ISSN 1444-0903.
- Graudins, Andis; Pham, Hanh Ngoc; Salonikas, Chris; Chan, Daya (2009). "Early presentation following overdose of modified-release paracetamol (Panadol Osteo) with biphasic and prolonged paracetamol absorption". New Zealand Medical Journal 122 (1300): 64–71. ISSN 1175-8716.
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