Duct of Bellini

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Duct of Bellini
Kidney-Tubules.gif
Position of the duct of Bellini in the kidney
Latin ductus papillaris
Gray's p.1223
Anatomical terminology

The duct of Bellini is an anatomical structure of the kidneys, also known as papillary (collecting) duct.

Structure[edit]

The straight or collecting tubes commence in the radiate part of the renal cortex, where they receive the curved ends of the distal convoluted tubules.

They unite at short intervals with one another, the resulting tubes presenting a considerable increase in caliber, so that a series of comparatively large tubes passes from the bases of the medullary rays into the renal pyramids.

In the medulla the tubes of each pyramid converge to join a central tube, the duct of Bellini, which finally opens on the summit of one of the renal papillae; the contents of the tube are therefore discharged into one of the renal calyces.

Clinical relevance[edit]

Cancer of Bellini's Duct[edit]

Collecting duct, or Bellini's duct, carcinoma is a relatively rare subtype of renal cell carcinoma (RCC), accounting for less than 1% of all RCCs.[1][2][3][4][5][6] Many reported cases have occurred in younger patients, often in the third, fourth, or fifth decade of life.[7] Collecting duct carcinomas are derived from the medulla, but many are infiltrative, and extension into the cortex is common.[8] Most reported cases have been high grade and advanced stage and have not responded to conventional therapies.[9][10][11][12][13] Most patients are symptomatic at presentation.[14] Immunohistochemical and molecular analyses suggest that collecting duct RCC may resemble transitional cell carcinoma, and some patients with advanced collecting duct RCC have responded to cisplatin- or gemcitabine-based chemotherapy.[15][16]

History[edit]

Eponym[edit]

So named in honor of its discoverer, Italian anatomist Lorenzo Bellini (1643–1704).

References[edit]

This article incorporates text from a public domain edition of Gray's Anatomy.

  1. ^ Kennedy et al., 1990[full citation needed]
  2. ^ Rumpelt et al., 1991[full citation needed]
  3. ^ Carter et al., 1992[full citation needed]
  4. ^ Störkel et al., 1997[full citation needed]
  5. ^ Srigley and Eble, 1998[full citation needed]
  6. ^ Swartz et al., 2002[full citation needed]
  7. ^ Carter et al., 1992[full citation needed]
  8. ^ Pickhardt et al., 2001[full citation needed]
  9. ^ Carter et al., 1992[full citation needed]
  10. ^ Chao et al., 2002b[full citation needed]
  11. ^ Polascik et al., 2002[full citation needed]
  12. ^ Mejean et al., 2003[full citation needed]
  13. ^ Tokuda et al., 2004[full citation needed]
  14. ^ Tokuda et al., 2004[full citation needed]
  15. ^ Milowsky et al., 2002[full citation needed]
  16. ^ Peyromaure et al., 2003[full citation needed]