Parathyroid hormone 2 receptor

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Parathyroid hormone 2 receptor
Symbols PTH2R ; PTHR2
External IDs OMIM601469 MGI2180917 HomoloGene3701 IUPHAR: 332 GeneCards: PTH2R Gene
RNA expression pattern
PBB GE PTHR2 206772 at tn.png
More reference expression data
Species Human Mouse
Entrez 5746 213527
Ensembl ENSG00000144407 ENSMUSG00000025946
UniProt P49190 Q91V95
RefSeq (mRNA) NM_005048 NM_139270
RefSeq (protein) NP_005039 NP_644676
Location (UCSC) Chr 2:
209.22 – 209.72 Mb
Chr 1:
65.28 – 65.39 Mb
PubMed search [1] [2]

Parathyroid hormone 2 receptor is a protein that in humans is encoded by the PTH2R gene[1]


The protein encoded by this gene is a member of the G protein-coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone 1 receptor (PTH1R). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.