Parathyroid hormone 2 receptor

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Parathyroid hormone 2 receptor
Identifiers
Symbols PTH2R ; PTHR2
External IDs OMIM601469 MGI2180917 HomoloGene3701 IUPHAR: PTH2 GeneCards: PTH2R Gene
RNA expression pattern
PBB GE PTHR2 206772 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5746 213527
Ensembl ENSG00000144407 ENSMUSG00000025946
UniProt P49190 Q91V95
RefSeq (mRNA) NM_005048 NM_139270
RefSeq (protein) NP_005039 NP_644676
Location (UCSC) Chr 2:
209.22 – 209.72 Mb
Chr 1:
65.28 – 65.39 Mb
PubMed search [1] [2]

Parathyroid hormone 2 receptor is a protein that in humans is encoded by the PTH2R gene[1]

Function[edit]

The protein encoded by this gene is a member of the G protein-coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone 1 receptor (PTH1R). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas.[1]

See also[edit]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.