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|Finless sole, Pardachirus marmoratus|
Pardachirus marmoratus, also known as the finless sole or the Red Sea Moses sole is a small fish from the Red Sea that secretes an ichthyotoxic milky substance from the base of its dorsal and anal fins. This secretion contains pardaxin, a lipophillic peptide that causes severe plasma membrane disruption resulting in cell leakage. The pardaxin containing secretion is used as a defensive mechanism against predators including sharks. Pardaxin is irritating to predator fish, particularly affecting the sensitive gills. Dr. Eugenie Clark conducted much of the early work on Pardachirus marmoratus.
There is much biotechnological interest in pardaxin, early interest focused on potential shark repellent applications while newer research foucuses on antimicrobial and neurotoxic potential of pardaxin and its analogues.
- Froese, Rainer and Pauly, Daniel, eds. (2012). "Pardachirus marmoratus" in FishBase. December 2012 version.
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