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Patho-biotechnology,[1][2][3] coined by Roy Sleator and Colin Hill (University College Cork, Ireland), describes the exploitation of pathogenic stress survival factors in biotechnology, medicine and food.

This approach shows promise for the development of novel vaccine and drug delivery systems, as well as the design of more technologically robust and effective probiotic cultures with improved biotechnological and clinical applications.


  1. ^ Sleator RD, Hill C (2007). "Patho-biotechnology; using bad bugs to make good bugs better". Sci Prog 90 (Pt 1): 1–14. doi:10.3184/003685007780440530. PMID 17455762. 
  2. ^ Sleator RD, Hill C (Apr 2006). "Patho-biotechnology: using bad bugs to do good things". Current Opinion in Biotechnology 17 (2): 211–6. doi:10.1016/j.copbio.2006.01.006. PMID 16459072. 
  3. ^ Sleator RD, Hill C (2008). "'Bioengineered Bugs' - a patho-biotechnology approach to probiotic research and applications". Med Hypotheses 70 (1): 167–9. doi:10.1016/j.mehy.2007.03.008. PMID 17452084. 

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