The pathogenesis of a disease is the mechanism that causes the disease. The term can also describe the origin and development of the disease, and whether it is acute, chronic, or recurrent. The word comes from the Greek pathos ("disease") and genesis ("creation").
Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. Lucy S. Tompkins, a professor of medicine at Stanford University focuses her research on bacterial pathogenesis, the mechanism by which bacteria cause infectious illness.
Most diseases are caused by multiple processes. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression).
- Fox, Alvin (2010). General aspects of bacterial pathogenesis. University of South Carolina School of Medicine: Microbiology and Immunology On-line Textbook.
- Haugan, Salomon Avian Influenza: Etiology, Pathogenesis and Interventions (Public Health in the 21st Century. Nova Science Pub Inc. January 30, 2010) ISBN 1-60741-846-0, ISBN 978-1-60741-846-7
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