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The pejorative suffix may add the sense of "a despicable example of the preceding," as in Spanish -ejo (see below). It can also convey the sense of "a despicable human having the preceding characteristic"; for instance, as in English -el (see below) or the development of the word cuckold from Old French cocu "cuckoo" + -ald, taken into Anglo-Saxon as cokewald and thus to the modern English word.
Examples of the pejorative suffix:
-alla -alles Suffixed to nouns gives new nouns. Examples: gentalla (from gent "people"). It's also used as a collective (group) suffix.
-arro -arros (fem. -arra -arres) Suffixed to nouns gives new nouns. Example: veuarra (from veu "voice"). It's also used as an augmentative suffix.
-astre -astres (fem. -astra -astres) Suffixed to nouns gives new nouns. Example: poetastra (from poeta "poet"). This suffix has also the meaning "indirect relation with".
-ot -ots (fem. -ota -otes) Suffixed to nouns gives new nouns. Example: sabatot (from sabata "shoe"). Suffixed to adjectives gives new adjectives. Example: lletjot (from lleig "ugly"). As a suffix it also means "object", giving a lexicalized word.
-erd, e.g. stouterd "naughty one" (from stout "naughty")
-erik, e.g. viezerik "filthy person" (from vies "dirty")
-tard, e.g. Paultard, conspiratard, libtard--new productive suffix from combination of retard and similarity to non-productive suffix -ard
-aster, e.g. poetaster, philosophaster (via Latin)
-ster, e.g. hipster, oldster (via Old English)
-ite, e.g. Paysleyite, Shiite (a follower or adherent of a person or doctrine; deprecatory term often given by opponents)
-nik, e.g. peacenik, neatnik (via Yiddish or Russian, where it is not necessarily pejorative)
-rel, e.g. mongrel, wastrel (from Middle English, from Old French)
-er, e.g. stoner, goner, beaner, truther, birther (not to be confused with other -er suffixes, e.g. occupation or comparative)
-aĉ-, e.g. veteraĉo "foul weather" (from vetero "weather")
-ald/-ard/-aud, e.g. salaud "dirty person (from sale "dirt")
-ā (-wā), e.g. lonoā "gossip" (from lono "news")
-ea, e.g. poluea "seasickness" (from polu "wet)
-accio(a) (or -uccio/a), e.g. boccaccia "ugly mug" (from bocca "mouth")
-目 (-me), e.g. 「化け物目」 (bakemono-me) "That damn monster!" or 「可愛いやつ目」 kawaii yatsu-me "That darn cutie!"
-aster, denoting fraudulent resemblance, e.g. patraster "one who plays the father" (from pater "father")
-ish, e.g. animosh "dog"
-asso, e.g. vidasso "wretched life" (from vido "life")
-iška (ишка) 
-uxa (уха), pejorative for non-personal nouns, e.g. černuxa, dramatic term for an unrelentingly bleak cinematic style (from čern- "black")
-jaga (яга), pejorative for persons, e.g. skuperdjaga (miser or skinflint), skromnjaga (excessively modest person), stiljaga (style-hunter, hipster), dokhodjaga (goner, said of Kolyma labor-camp prisoners nearing death)
-aco(a), e.g. pajarraco "large ugly bird" (from pajaro "bird)
-ejo(a), e.g. lugarejo "podunk town" (from lugar "place") and librejo "worthless book" (from libro "book"); however, -ejo can also show endearment, as in festejo.
-ote(a), e.g. discursote "long dull speech" (from discurso "speech")(used mostly as an augmentative)
-ucho (a), e.g. casucha "hovel" (from casa "house")
-zuelo (a), e. g. mujerzuela "whore" (from mujer "woman")