Pemphigoid

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Pemphigoid
Classification and external resources
ICD-10 L12
ICD-9 694.5
DiseasesDB 9760
MeSH D010391

Pemphigoid is a group of uncommon and rare autoimmune blistering skin diseases. As its name indicates, pemphigoid is similar in general appearance to pemphigus,[1] but, unlike pemphigus, pemphigoid does not feature acantholysis, a loss of connections between skin cells.[2]

Pemphigoid is more common than pemphigus, and is slightly more common in women than in men. It is also more common in people over 60 years of age than it is in younger people.

Classification[edit]

IgG[edit]

The forms of pemphigoid are considered to be connective tissue autoimmune skin diseases. There are several types:

Bullous and Cicatricial pemphigoids usually affect persons who are over age 60.[3][4] Gestational pemphigoid occurs during pregnancy,[5] typically in the second or third trimester, and/or immediately following pregnancy.

IgA[edit]

Pemphigoid is usually considered to be mediated by IgG, but IgA-mediated forms have also been described.[6]

IgA Pemphigoid rarely affect the mouth.

See also[edit]

External links[edit]

References[edit]

  1. ^ "pemphigoid" at Dorland's Medical Dictionary
  2. ^ Pemphigoid at the US National Library of Medicine Medical Subject Headings (MeSH)
  3. ^ Cicatricial Pemphigoid at eMedicine
  4. ^ Bullous Pemphigoid at eMedicine
  5. ^ Pemphigoid Gestationis at eMedicine
  6. ^ Thomas T. Provost; John A. Flynn (2001). Cutaneous medicine: cutaneous manifestations of systemic disease. PMPH-USA. pp. 209–. ISBN 978-1-55009-100-7. Retrieved 25 June 2010.