Pentalofos (Greek: Πεντάλοφος) is a village and a former community in Kozani regional unit, West Macedonia, Greece. Since the 2011 local government reform it is part of the municipality Voio, of which it is a municipal unit. It is located at 1060 meters elevation to the base of mountain Voio. The population of the municipal unit was 620 people, while the popualation of the community itself was 446 people as of 2011. (2001).