Pentolinium

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Pentolinium
Pentolinium.png
Systematic (IUPAC) name
1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium
Clinical data
Legal status
?
Identifiers
CAS number 144-44-5
52-62-0 (tartrate salt)
ATC code ?
PubChem CID 5850
DrugBank DB01090
ChemSpider 5641
UNII ULL76WPU5X
ChEMBL CHEMBL1271
Chemical data
Formula C15H32N2 
Mol. mass 240.43 g/mol

Pentolinium is a ganglionic blocking agent which acts as a nicotinic acetylcholine receptor antagonist. It can be used as an antihypertensive drug during surgery or to control hypertensive crises. It works by binding to the acetylcholine receptor of adrenergic nerves and thereby inhibiting the release of noradrenaline and adrenaline. Blocking this receptor leads to smooth muscle relaxation and vasodilatation. Pentolinium can be given orally, injected intramuscularly or administered intravenously.[citation needed]

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