Born Curtis Arnoux Peters, Jr. in New York, New York, and educated at the Hotchkiss School and Yale University, his cartoons were published in The New Yorker from 1925–1968. They often depicted a cross-section of New York society from the 1920s through the 1960s. He married The New Yorker magazine columnist and fashion editor Lois Long and together they had one daughter, Patricia Arno, born September 18, 1928. Their marriage ended in 1930. Arno died on February 22, 1968 at the age of 64. He is interred at Kensico Cemetery in Valhalla, New York.