Phenampromide

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Phenampromide
Phenampromide.svg
Systematic (IUPAC) name
N-(1-methyl-2-piperidin-1-ylethyl)-N-phenylpropanamide
Clinical data
Legal status Prohibited (S9) (AU)
Identifiers
CAS number 129-83-9 N
ATC code None
PubChem CID 8523
ChemSpider 16735960 YesY
UNII 0600L2M6EZ YesY
Chemical data
Formula C17H26N2O 
Mol. mass 274.40 g/mol
 N (what is this?)  (verify)

Phenampromide is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and diampromide. It was invented in the 1960s[1] by American Cyanamid Co.[2] Although never given a general release, it was trialled and 50mg codeine ≈ 60mg phenampromide. Tests on the 2 isomers showed that all of the analgesic effects were caused by the (S) isomer.

Phenampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea.

References[edit]

  1. ^ Portoghese PS. Stereochemical Studies on Medicinal Agents II. Absolute Configuration of (-)-Phenampromide. Journal of Medicinal Chemistry. 1965 Mar;8:147-50.
  2. ^ US Patent 3016382