Phenethyl isothiocyanate

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Phenethyl isothiocyanate
Phenethyl isothiocyanate.svg
Names
IUPAC name
(2-Isothiocyanatoethyl)benzene
Other names
Phenylethyl isothiocyanate; Phenethyl mustard oil
Identifiers
Abbreviations PEITC
CAS number 2257-09-2 N
ChEBI CHEBI:351346 YesY
ChEMBL ChEMBL151649 YesY
ChemSpider 15870 YesY
Jmol-3D images Image
PubChem 16741
Properties
C9H9NS
Molar mass 163.24 g·mol−1
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Phenethyl isothiocyanate (PEITC) is a naturally occurring isothiocyanate that is found in some cruciferous vegetables.[1] PEITC has been studied for its potential for chemoprevention.[2][3][4]

In terms of biosynthesis, PEITC is produced from gluconasturtiin by the action of the enzyme myrosinase.

References[edit]

  1. ^ "Dictionary of Cancer Terms: PEITC". National Cancer Institute. 
  2. ^ Wang, LG; Chiao, JW (2010). "Prostate cancer chemopreventive activity of phenethyl isothiocyanate through epigenetic regulation (review)". International Journal of Oncology 37 (3): 533–9. doi:10.3892/ijo_00000702. PMID 20664922. 
  3. ^ Cheung, KL; Kong, AN (2010). "Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention". The AAPS journal 12 (1): 87–97. doi:10.1208/s12248-009-9162-8. PMC 2811646. PMID 20013083. 
  4. ^ Kwon, Ki Han; Xu, Changjiang; Keum, Young-Sam; Khor, Tin Oo; Kim, Jung-Hwan; Huang, Mou-Tuan; Reddy, Bandaru S.; Li, Wenge; Kong, Ah-Ng Tony (2007). "Natural dietary phytochemicals: a promising future for cancer prevention and treatment of earlier lesion". Cancer: Disease Progression and Chemoprevention: 109–126.