|Jmol-3D images||Image 1|
|Molar mass||138.16 g mol−1|
|Appearance||Colorless oily liquid|
|Melting point||11 to 13 °C (52 to 55 °F; 284 to 286 K)|
|Boiling point||247 °C (477 °F; 520 K)|
|Flash point||113 °C (235 °F) (closed cup)|
|Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)|
|(what is: / ?)|
Phenoxyethanol is an organic chemical compound, a glycol ether often used in dermatological products such as skin creams and sunscreen. It is a colorless oily liquid. It is a bactericide (usually used in conjunction with quaternary ammonium compounds), often used in place of sodium azide in biological buffers because phenoxyethanol is less toxic and non-reactive with copper and lead. It is used in many applications such as cosmetics, vaccines and pharmaceuticals as a preservative.
It is also used as a fixative for perfumes, an insect repellent, a topical antiseptic, a solvent for cellulose acetate, some dyes, inks, and resins, in preservatives, pharmaceuticals, and in organic synthesis. It is moderately soluble in water. It is used as an anesthetic in the aquaculture of some fish.
The Food and Drug Administration has warned that the chemical is toxic to infants via ingestion, and "can depress the central nervous system and may cause vomiting and diarrhea." Combined with Chlorphenesin, these two chemicals can cause respiratory depression in infants. Since these chemicals are often present in cosmetics and lotions applied to the hands and are easily ingested, caution should be exercised.
- Tsantilas, H.; Galatos, A.D.; Athanassopoulou, F.; Prassinos, N.N.; Kousoulaki, K. (2006). "Efficacy of 2-phenoxyethanol as an anaesthetic for two size classes of white sea bream, Diplodus sargus L., and sharp snout sea bream, Diplodus puntazzo C". Aquaculture 253: 64. doi:10.1016/j.aquaculture.2005.07.034.
- Mylonas C., Cardilanetti G., Sigelaki I., Polzonetti-Magni A. (2005). "Comparative efficacy of clove oil and 2-phenoxyethanol as anesthetics in the aquaculture of european sea bass (Dicentrarchus labrax) and gilthead sea bream (Sparus aurata) at different temperatures". Aquaculture 246 (1–4): 467–481. doi:10.1016/j.aquaculture.2005.02.046.
- CDC excipient table
- Tokunaga, H. T. (2003). "Studies for analyzing phenoxyethanol and parabens in commercial lotions" (Free full text). Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences (121): 25–29. ISSN 1343-4292. PMID 14740401.
- Lowe I, Southern J (1994). "The antimicrobial activity of phenoxyethanol in vaccines". Lett Appl Microbiol 18 (2): 115–6. doi:10.1111/j.1472-765X.1994.tb00820.x. PMID 7764595.
- Wineski LE, English AW (1989). "Phenoxyethanol as a nontoxic preservative in the dissection laboratory". Acta Anat (Basel) 136 (2): 155–8. doi:10.1159/000146816. PMID 2816264.
- Zug KA, Warshaw EM, Fowler JF Jr, Maibach HI, Belsito DL, Pratt MD, Sasseville D, Storrs FJ, Taylor JS, Mathias CG, Deleo VA, Rietschel RL, Marks J. Patch-test results of the North American Contact Dermatitis Group 2005–2006. Dermatitis. 2009 May–Jun;20(3):149-60.
- "FDA Warns Consumers Against Using Mommy's Bliss Nipple Cream".