Benzyl methyl ketone; Methyl benzyl ketone; Phenyl-2-propanone
|Molar mass||134.18 g·mol−1|
|Appearance||Colorless, pleasant odor|
|Melting point||−15 °C (5 °F; 258 K)|
|Boiling point||214 °C (417 °F; 487 K)|
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
|what is: / ?)(|
Phenylacetone is an organic compound with the chemical formula C6H5CH2C(O)CH3. It is a colorless oil that is soluble in organic solvents. This substance is used in the manufacture of methamphetamine and amphetamine, where it is commonly known as P2P. Due to the illicit uses in clandestine chemistry, it was declared a schedule II controlled substance in the United States in 1980. In humans, phenylacetone occurs as a metabolite of amphetamine via oxidative deamination.
- C6H5CH2CO2H + CH3CO2H → C6H5CH2C(O)CH3 + CO2 + H2O
Due to its status as a controlled substance, other laboratory scale methods have been reported. It can be produced by the condensation of benzaldehyde with nitroethane, which yields phenyl-2-nitropropene followed by reduction, usually in the presence of acid, to phenylacetone.
This is, however, typically not used due to overalkylation commonly associated with Friedel-Crafts alkylation.
- MDP2P - related compound with a methylenedioxy group, and a precursor to MDMA.
- Cyclohexylacetone - the cyclohexane derivative of phenylacetone
- "Lists of: Scheduling Actions, Controlled Substances, Regulated Chemicals" (PDF). U.S. Department of Justice, Drug Enforcement Administration.
- Siegel, H.; Eggersdorfer, M. (2005), "Ketones", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, doi:10.1002/14356007.a15_077
- Synthesis of Phenyl-2-Propanone (P2P)