Philip Palmer Green

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Philip Palmer Green is a theoretical and computational biologist noted for developing important algorithms and procedures used in Gene mapping and DNA sequencing. He earned his doctorate from Berkeley in mathematics in 1976 with a dissertation on C*-algebra under the direction of Marc Rieffel, but, like his colleague Eric Lander, transitioned from pure mathematics into applied work in biology and bioinformatics. Green has obtained numerous important results, including in developing Phred,[1] a widely used DNA trace analyzer,[2][3] in mapping techniques,[4] and in genetic analysis.[5][6] Green was elected to the National Academy of Sciences in 2001 and won the Gairdner Award in 2002.[7]

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  1. ^ Ewing, B., Hillier, L., Wendl, M.C., and Green, P. (1998) Base-calling of automated sequencer traces using phred. I. Accuracy assessment. Genome Res. 8(3), 175–185. PMID 9521921 full article
  2. ^ Koboldt, D. C. and Miller, R. D. (2011) Identification of Polymorphic Markers for Genetic Mapping, chapter 2 in "Genomics: Essential Methods", John Wiley and Sons.
  3. ^ Highsmith, W. E. (2006) Electrophoretic Methods for Mutation Detection and DNA Sequencing, chapter 9 in "Molecular Diagnostics for the Clinical Laboratorian", Humana Press
  4. ^ Lander, E.S. and Green, P. (1987) Construction of multilocus genetic-linkage maps in humans. PNAS 84(8), 2363–2367.
  5. ^ Ewing, B. and Green, P. (2000) Analysis of expressed sequence tags indicates 35,000 human genes. Nature Genetics 25(2), 232–234.
  6. ^ Green, P. et al. (1993) Ancient conserved regions in new gene-sequences and the protein databases. Science 259(5102), 1711–1716.
  7. ^ National Academy of Sciences (2004) Biography of Phil Green. PNAS 101(39), 13991–13993.

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