Pholedrine

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Pholedrine
Pholedrine2D.svg
Systematic (IUPAC) name
4-[2-(methylamino)propyl]phenol
Clinical data
Legal status
?
Routes Topical (Ocular)
Identifiers
CAS number 370-14-9 YesY
ATC code ?
PubChem CID 4655
ChemSpider 4494 N
UNII AY28O44JGD YesY
KEGG D08370 YesY
Chemical data
Formula C10H15NO 
Mol. mass 165.2322 g/mol
 N (what is this?)  (verify)

Pholedrine ('Paredrinol, Pulsotyl, Veritol), also known as 4-hydroxy-N-methylamphetamine (4-HMA), 4-hydroxymethamphetamine, and para-hydroxymethamphetamine,[1] is a drug that stimulates the sympathetic nervous system.[2] It is administered as a topical eye drop form for the purpose of dilating the pupil and can be used to diagnose Horner's syndrome.[2]

Metabolic pathways of methamphetamine

Pholedrine is one of methamphetamine's two immediate metabolites in humans.

See also[edit]

References[edit]

  1. ^ http://www.chemicalbook.com/ProductChemicalPropertiesCB6216212_EN.htm
  2. ^ a b Bates, A. T.; Chamberlain, S.; Champion, M.; Foley, L.; Hughes, E.; Jani, B.; Mehta, H.; Smith, S. E. (1995). "Pholedrine: A substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome". Journal of neurology, neurosurgery, and psychiatry 58 (2): 215–217. doi:10.1136/jnnp.58.2.215. PMC 1073320. PMID 7876854.  edit