Phorate

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Phorate
Phorate.svg
Names
IUPAC name
O,O-Diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate
Other names
Thimet (trademark)
Identifiers
298-02-2 YesY
ChEBI CHEBI:38764 N
ChEMBL ChEMBL510014 N
ChemSpider 4626 YesY
Jmol-3D images Image
PubChem 4790
Properties
C7H17O2PS3
Molar mass 260.38 g·mol−1
Appearance Colorless liquid
Odor Skunk-like[1]
Density 1.16 g/mL
Melting point −43 °C; −45 °F; 230 K [1]
0.005% (20°C)[1]
Vapor pressure 0.0008 mmHg (20°C)[1]
Hazards
Flash point 160 °C; 320 °F; 433 K (open cup)[1]
US health exposure limits (NIOSH):
none[1]
TWA 0.05 mg/m3 ST 0.2 mg/m3 [skin][1]
N.D.[1]
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N verify (what isYesY/N?)
Infobox references

Phorate is an organophosphate used as an insecticide and acaricide. At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including human. It inhibits acetylcholinesterase and pseudocholinesterase.[2]

Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.[2]

Phorate is absorbed readily through all ways. Its toxicity is high. Oral LD50 to rats is 1.1 – 3.2 mg/kg, to mice 3.5 – 6.5 mg/kg (technical phorate). Similar values has been found out to birds.[2]

References[edit]

  1. ^ a b c d e f g h "NIOSH Pocket Guide to Chemical Hazards #0502". National Institute for Occupational Safety and Health (NIOSH). 
  2. ^ a b c Data sheets on pesticides No. 75 – Phorate

External Links[edit]

  • Phorate in the Pesticide Properties DataBase (PPDB)