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|Jmol-3D images||Image 1|
|Molar mass||390.07 g/mol|
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate.
It plays a role in transferring phospho-ribose groups in several reactions:
Increased levels of PRPP are present in Lesch-Nyhan Syndrome. Decreased levels of hypoxanthine guanine phosphoribosyl transferase (HGPRT) causes this accumulation, as PRPP is a substrate used by HGPRT during purine salvage.
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