Phyllanthus niruri

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Chanca piedra
Scientific classification
Kingdom: Plantae
(unranked): Angiosperms
(unranked): Eudicots
(unranked): Rosids
Order: Malpighiales
Family: Phyllanthaceae
Genus: Phyllanthus
Species: P. niruri
Binomial name
Phyllanthus niruri
L.
Synonyms

Phyllanthus amarus

The annual herb Phyllanthus niruri is best known by the common names Stonebreaker(Eng.), Chanca Piedra(Sp.) and Quebra Pedra(Port.), Seed-Under-Leaf(Eng.) but has many other common names in assorted languages, including dukong anak, dukong-dukong anak, amin buah, rami buah, turi hutan, bhuiaonla, Meniran (Indonesia), കീഴാനെല്ലി (Malayalam) and கீழாநெல்லி / Keela Nelli (Tamil).The herb is known as Nela Nelli in Kannada and "Nela Usiri" in Telugu. It is a widespread tropical plant commonly found in coastal areas. It is a relative of the spurges, belonging to the leafflower genus of Family Phyllanthaceae.

Contents

[edit] Growth

Phyllanthus niruri

It grows 50 to 70 centimeters tall and bears ascending herbaceous branches. The bark is smooth and light green. It bears numerous pale green flowers which are often flushed with red. The fruits are tiny, smooth capsules containing seeds.

[edit] Medicinal uses

Some of the medicinal properties suggested by preclinical trials are anti-hepatotoxicity,[1] anti-lithic, anti-hypertensive, anti-HIV and anti-hepatitis B.[2][3] However, human trials do not show efficacy against hepatitis B virus.[4]

P. amarus is an important plant of Indian Ayurvedic system of medicine which is used for stomach problems,and for the genitourinary system, liver, kidney and spleen.[5]The plant has long been used in Brazil and Peru as a supposed herbal remedy for kidney stones. Research among sufferers of kidney stones has shown that, while intake of Phyllanthus niruri didn't lead to a significant difference in either stone voiding or pain levels, it may reduce urinary calcium, a contributing factor to stone growth.[6] One study conducted on rats showed that an aqueous solution of Phyllanthus niruri may inhibit kidney stone growth and formation in animals who already have stones.[7],[8]

[edit] References

  1. ^ Ravikumar YS, Ray U, Nandhitha M, Perween A, Naika HR, Khanna N, Das S.,"Inhibition of Hepatitis C virus replication by herbal extract: Phyllanthus amarus as potent natural source." Virus Res. 2011 Mar 23;
  2. ^ Bagalkotkar G, Sagineedu SR, Saad MS, Stanslas J (December 2006). "Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review". The Journal of Pharmacy and Pharmacology 58 (12): 1559–70. doi:10.1211/jpp.58.12.0001. PMID 17331318. 
  3. ^ Naik AD, Juvekar AR (September 2003). "Effects of alkaloidal extract of Phyllanthus niruri on HIV replication". Indian Journal of Medical Sciences 57 (9): 387–93. PMID 14515028. http://www.indianjmedsci.org/article.asp?issn=0019-5359;year=2003;volume=57;issue=9;spage=387;epage=93;aulast=Naik. Retrieved 2009-06-20. 
  4. ^ http://healthlibrary.epnet.com/GetContent.aspx?token=e0498803-7f62-4563-8d47-5fe33da65dd4&chunkiid=21845#P2 What Is the Scientific Evidence for Phyllanthus?
  5. ^ Jay Ram Patela, Priyanka Tripathib, Vikas Sharmaa, Nagendra Singh Chauhana, Vinod Kumar Dixita, "Phyllanthus amarus: Ethnomedicinal uses, phytochemistry and pharmacology: A review" Journal of Ethnopharmacology doi:10.1016/j.jep.2011.09.040 |http://www.sciencedirect.com/science/article/pii/S0378874111007112
  6. ^ Nishiura JL, Campos AH, Boim MA, Heilberg IP, Schor N (October 2004). "Phyllanthus niruri normalizes elevated urinary calcium levels in calcium stone forming (CSF) patients". Urological Research 32 (5): 362–6. doi:10.1007/s00240-004-0432-8. PMID 15221244. 
  7. ^ Freitas AM, Schor N, Boim MA (June 2002). "The effect of Phyllanthus niruri on urinary inhibitors of calcium oxalate crystallization and other factors associated with renal stone formation". BJU International 89 (9): 829–34. doi:10.1046/j.1464-410X.2002.02794.x. PMID 12010223. http://www3.interscience.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=1464-4096&date=2002&volume=89&issue=9&spage=829. Retrieved 2009-06-20. 
  8. ^ Boim MA, Heilberg IP, Schor N"Phyllanthus niruri as a promising alternative treatment for nephrolithiasis." Int Braz J Urol. 2010 Nov-Dec;36(6):657-64; discussion 664

[edit] External links


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