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Chemical structure of hyllodulcin
CAS number 21499-23-0 YesY
PubChem 146694
Jmol-3D images Image 1
Molecular formula C16H14O5
Molar mass 286.27 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Phyllodulcin is an dihydroisocoumarin found in Hydrangea macrophylla[1] and Hydrangea serrata.[2] It is a sweetener 400-800 sweeter than sugar. [3]

See also[edit]


  1. ^ Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Matsuda H., Shimoda H., Yamahara J. and Yoshikawa M., Biological & pharmaceutical bulletin, 1999, vol. 22, no8, pp. 870-872, INIST:1959604
  2. ^ Accumulation of phyllodulcin in sweet-leaf plants of Hydrangea serrata and its neutrality in the defence against a specialist leafmining herbivore. Mami Ujihara, Masateru Shinozaki and Makoto Kato, Researches on population ecology, Volume 37, Number 2, pp. 249-257, doi:10.1007/BF02515827
  3. ^ Chemical and Functional Properties of Food Saccharides. P. Tomasik, CRC Press, Boca Raton, 2003 , isbn : 978-0-8493-1486-5