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Physical effect may refer to:
- a named phenomenon within the field of physics, such as the Doppler effect or the Photoelectric effect,
- more generally, any consequence of some cause which is related to the material world (physis),
- in medicine, a change in the functioning of the body, as opposed to psychological or emotional effects, e.g. as a result of a disease, treatment or drug intake,
- a certain type of special effect.
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