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|Look up picayune in Wiktionary, the free dictionary.|
A picayune is an obsolete Spanish coin.
As the coin was of little value, picayune also came to mean "trivial" or "of little value".
Picayune may also refer to:
- The Times-Picayune, a daily newspaper published in New Orleans, Louisiana, United States
- The Bloom Picayune, a fictional newspaper appearing in the Bloom County cartoon strip
- Picayune, Mississippi, a city in the southern United States
- Picayune Strand State Forest, a protected area near Naples, Florida, United States
- John "Picayune" Butler, an influential black entertainer who lived in 19th century New Orleans
- Picayune cigarettes, a strong-tasting now-defunct brand previously marketed by Liggett & Myers
- Picayune Rancheria of Chukchansi Indians, the home of a federally recognized tribe of indigenous people of California
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