Bisoli started his professional career in 1984 with Pistoiese, where he spent a total of three seasons. He then played for a handful of minor teams before to join Cagliari in 1991, becoming a mainstay for the Sardinians. He spent six seasons for the rossoblu, marking a total of 167 appearances and also taking part in the club's 1994–95 UEFA Cup stint. In 1997, he moved to newly promoted Serie A team Empoli, where he played for two seasons. He then played for Perugia, Brescia and Pistoiese before to retire in 2003 after a season with amateur hometown club Porretta.
Following his retirement from active football, Bisoli accepted an assistant coaching role at Fiorentina, working alongside head coach Emiliano Mondonico during the 2004–05 season. He then became head coach of Serie C2 team Prato, where he worked for two seasons. From 2007 he is head coach of newly promoted Serie C1 side Foligno, where he surprisingly managed to win a promotion playoff spot in his first season with the club, and then achieving a promotion playoff spot in his second season with the Umbrian minnows. From July 2008 he is head coach of Cesena in the former Serie C1, now rebranded as Lega Pro Prima Divisione, managing to guide the bianconeri to win the league title in his first season in charge of the club.
He was confirmed head coach of Cesena also for the 2009–10 season, which proved to be a very successful one as the club from Romagna managed to join the race for direct promotion to Serie A, a league Cesena has not played in since 1991. He ultimately managed to guide Cesena to a historical promotion in the final game of the season, after the Bianconeri from Romagna ended the league in second place, thus ending a 19-year absence from the top flight for his club. He left Cesena at the end of the season to join his former club Cagliari, agreeing a contract with the Sardinian Serie A club. His experience at Cagliari as head coach however proved to be highly unsuccessful, and he was ultimately dismissed on 15 November 2010 after a 0–1 home loss that left the Sardinians in 19th place.
On 26 May 2011 Bisoli was named as the new coach of Bologna, but he was sacked on 4 October 2011, with the club the bottom of the table and replaced by Stefano Pioli.