Pirbuterol

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For other uses, see Maxair.
Pirbuterol
Pirbuterol.png
Pirbuterol ball-and-stick.png
Systematic (IUPAC) name
(RS)-6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol
Clinical data
Trade names Maxair
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a601096
Pregnancy cat.
  • C
Legal status
Routes Inhalational
Identifiers
CAS number 38029-10-6 N
ATC code R03AC08 R03CC07
PubChem CID 4845
DrugBank DB01291
ChemSpider 4679 YesY
UNII OG645J8RVW YesY
KEGG D08387 N
ChEMBL CHEMBL1094966 YesY
Chemical data
Formula C12H20N2O3 
Mol. mass 240.30 g/mol
300.3 g/mol (acetate)
 N (what is this?)  (verify)

Pirbuterol (trade name: Maxair) is a beta-2 adrenergic bronchodilator used in the treatment of asthma, available (as pirbuterol acetate) as a breath-activated metered-dose inhaler ("autohaler").

Clinical use[edit]

  • Asthma - preventative/maintenance medicine
  • Asthma - "rescue" medicine for reversal of acute asthma attack

Mode of action[edit]

Further information: Beta2-adrenergic agonist

Adverse effects[edit]

Further information: Beta2-adrenergic agonist

Synthesis[edit]

Pirbuterol synthesis:[1][2][3][4][5][6][7]

Source/external link[edit]

References[edit]

  1. ^ W.E. Barth, U.S. Patent 3,700,681 (1972).
  2. ^ W. Barth, U.S. Patent 3,763,173 (1973).
  3. ^ W. Barth, U.S. Patent 3,772,314 (1973).
  4. ^ W. Barth, U.S. Patent 3,786,160 (1974).
  5. ^ S. Nakanishi, U.S. Patent 3,948,919 (1976).
  6. ^ S. Nakanishi, U.S. Patent 4,031,108 (1977).
  7. ^ W.E. Barth, DE 2204195  (1972).