Pirlimycin

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Pirlimycin
Pirlimycin structure.svg
Systematic (IUPAC) name
Methyl(2S-cis)-7-chloro-6,7,8-trideoxy-6[[(4-ethyl-2-piperidinyl) carbonyl]amino]-1-thio-L-threo-α-D-galacto-octopyranoside
Clinical data
Legal status
?
Routes Intramammary
Identifiers
CAS number 79548-73-5 YesY
ATCvet code QJ51FF90
UNII LM19JT6G5K N
KEGG D08391 YesY
ChEMBL CHEMBL1652611 N
Chemical data
Formula C17H31ClN2O5S 
Mol. mass 410.164 g/mol
 N (what is this?)  (verify)

Pirlimycin hydrochloride belongs to the lincosamide class of antimicrobials. Under the trade name Pirsue,[1] it is used in the treatment of mastitis in cattle.

Activity[edit]

Pirlimycin is active against Gram-positive bacteria, specifically Staphylococcus aureus and coagulase negative species of Staphylococcus and Streptococcus. It has no activity against Gram-negative bacteria.[2]

Mechanism of action[edit]

It is bacteriostatic and acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome.

References[edit]