Specifically, Piskacek's sign consists noting a palpable lateral bulge or soft prominence one of the locations where the uterine tube meets the uterus. Piskacek's sign can be noted in the seventh to eight week of gestation. Non pregnant uterus is pyriform in shape. By 12 weeks of gestation it becomes globular. In lateral implantation, there is asymmetrical enlargement of the uterus. One half of d uterus where the implantation occurred is firm while the other half is soft. This is known as Piskacek's sign. The sign is named after Ludwig Piskaçek.