It is noted for the extensive Plainville Turkey Farms, which remained in the same family from 1835 until recently. The business was sold in 2007 to Hain Capital Group. The former Plainville turkey processing operations were relocated to Pennsylvania in 2009, and the Plainville, NY plant was shut down in 2010.
Nearby on Route 370 west of the hamlet is the James Leslie Voorhees house, Whig Hill (1833), one of the major historic houses of Onondaga County. Voorhees was a wealthy landowner of nearby property and a builder of New York City as well as Central New York engineering projects who was active in New York State politics.