Plasminogen activator

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A plasminogen activator is a serine protease which converts plasminogen to plasmin, thus promoting fibrinolysis.

Types include:

It is inhibited by plasminogen activator inhibitor-1 and plasminogen activator inhibitor-2.

Plasminogen
Plasminogenpress.png
PDB rendering based on 4dur.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols PLG ; DKFZp779M0222
External IDs OMIM173350 MGI97620 HomoloGene55452 ChEMBL: 1801 GeneCards: PLG Gene
EC number 3.4.21.7
RNA expression pattern
PBB GE PLG 209978 s at tn.png
PBB GE PLG 209977 at tn.png
PBB GE PLG 205871 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5340 18815
Ensembl ENSG00000122194 ENSMUSG00000059481
UniProt P00747 P20918
RefSeq (mRNA) NM_000301 NM_008877
RefSeq (protein) NP_000292 NP_032903
Location (UCSC) Chr 6:
161.12 – 161.17 Mb
Chr 17:
12.38 – 12.42 Mb
PubMed search [1] [2]