Pleural disease

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Pleural disease
Classification and external resources
MeSH D010995

Pleural diseases include:

  • Pneumothorax: a collection of air within the pleural cavity, arising either from the outside or from the lung. Pneumothoraces may be traumatic, iatrogenic, or spontaneous. A tension pneumothorax is a particular type of pneumothorax where the air may enter (though a defect of the chest wall, lung, or airways) on inspiration, but cannot exit on expiration. Each breath increases the amount of trapped air in the chest cavity, leading to further lung compression. This is often an urgent situation and may progress to a medical emergency if there is compromise of the venous return to the heart causing hypotension and rarely shock.
  • Pleural effusion: a fluid accumulation within the pleural space. Abnormal collections of pleural fluid may be due to excessive fluid volume (i.e. excess intravenous fluids, renal failure), decreased fluid protein (e.g. cirrhosis, proteinuria), heart failure, bleeding (hemothorax), infections (parapneumonic effusions, pleural empyema), inflammation, malignancies, or perforation of thoracic organs (i.e. chylothorax, esophageal rupture).
  • Pleural tumors: abnormal growths on the pleurae. These may be benign (i.e. solitary fibromas) or malignant in nature. Pleural Mesothelioma is a type of malignant cancer associated with asbestos exposure.
  • Pleural plaques: discrete fibrous or partially calcified thickened area which can be seen on X-rays of individuals exposed to asbestos. Although pleural plaques are themselves asymptomatic, in some patients this develops into pleural thickening.

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