Plicatic acid

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Plicatic acid
Plicatic acid.svg
CAS number 16462-65-0 YesY
PubChem 104836
ChemSpider 94630 YesY
Jmol-3D images Image 1
Molecular formula C20H22O10
Molar mass 422.38 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Plicatic acid is a carboxylic acid from the resin acid group. It is naturally found in Thuja and cypress resin. It is the main irritant and contact allergen present in thuja wood. (Cf. pine, where the primary irritant is abietic acid.)

The highest concentrations of plicatic acid can be found in Thuja plicata (Western Redcedar), but Thuja occidentalis (Eastern Arborvitae) and Cryptomeria japonica (Sugi) contain it in significant proportions as well.

Exposure to plicatic acid or thuja wood dust can worsen asthma and provoke allergic reactions.[1]


  1. ^ Ayars, GH; Altman, LC; Frazier, CE; Chi, EY (1989). "The toxicity of constituents of cedar and pine woods to pulmonary epithelium". The Journal of allergy and clinical immunology 83 (3): 610–8. doi:10.1016/0091-6749(89)90073-0. PMID 2926083.