Polish Chileans include immigrants to Chile and their descendants who recognize their Polish ancestry.
A small number of Poles came to Chile, with first of them coming during the Napoleonic wars. In early 20th century, there were around 300 Poles in Chile. One of the most notable Polish Chileans, Ignacy Domeyko became chancellor of the University of Chile in that time. After World War II, 1947-1951, around 1,500 Poles, mostly former Zivilarbeiter (forced laborers in Nazi Germany), as well as former soldiers and inmates of Nazi concentration camps settled in Chile. In 1949 the Association of Poles in Chile was founded (reestablished formally as "Zjednoczenie Polskie w Chile im. Ignacego Domeyki" /Unión Polaca de Chile "Ignacio Domeyko" in 1992, president Andrzej Zabłocki ). A significant majority of Polish Chileans live in Santiago.
In addition, during the Interbellum around 1000 Polish Jews immigrated to Chile, mostly for economic reasons.
Another Polonia organization in Chile is Koło im. Jana Pawła II ("Pope John Paul II Circle"), chairman Ewa Odachowska 
Also, the Polish Catholic Mission (under Polish Episcopal Conference; pl:Polska Misja Katolicka) operates in Chile.
- Ignacy Domeyko, geologist
- Anita Domeyko (Ana Domeyko Alamos de Salazar, Anita Domeyko Alamos) (1902-2007), Polish-Chilean social activist (pl:Ana Domeyko)
- Igor Lichnovsky, Football player
- Rodrigo Goldberg, Football player
- Hans Podlipnik, Tennis player
- Marcos Libedinsky, former president of the Supreme Court of Chile
- Karen Poniachik, journalist; former Minister of Mining and Energy
- Michał Poradowski (1913-2003), Catholic priest, theologian, educator (pl:Michał Poradowski); Chilean resident 1950-1993, president of the Association of Poles in Chile (1951-1955)
- Clara Szczaranski, lawyer
- Luciano Kulczewki, architect
- Katty Kowaleczko, actress
- Anita Klesky, actress
- Francisco Kaminski, journalist