Polypyrimidine tract-binding protein

From Wikipedia, the free encyclopedia
Jump to: navigation, search
polypyrimidine tract binding protein 1
Symbol PTBP1
Alt. symbols PTB
Entrez 5725
HUGO 9583
OMIM 600693
RefSeq NM_002819
UniProt P26599
Other data
Locus Chr. 19 p13.3
polypyrimidine tract binding protein 2
Symbol PTBP2
Entrez 58155
HUGO 17662
OMIM 608449
RefSeq NM_021190
UniProt Q9UKA9
Other data
Locus Chr. 1 p21.3-22.1

Polypyrimidine tract-binding protein is an RNA-binding protein, also known as PTB or hnRNP I. PTB functions mainly as a splicing regulator, although it is also involved in alternative 3' end processing, mRNA stability and RNA localization.[1]

See also[edit]


  1. ^ Valcárcel J, Gebauer F (November 1997). "Post-transcriptional regulation: the dawn of PTB". Curr. Biol. 7 (11): R705–8. doi:10.1016/S0960-9822(06)00361-7. PMID 9382788. 

External links[edit]