Pores of Kohn

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The Pores of Kohn (also known as interalveolar connections) are discrete holes in walls of adjacent alveoli.[1] Cuboidal type II alveolar cell usually forms part of aperture.[2]

Etymology[edit]

The Pores of Kohn take their name from the German physician Hans Kohn [1866-1935] who first described them in 1893.[3]

Development[edit]

They are absent in human newborns. They develop at 3-4 years of age along with Canals of Lambert during process of thinning of alveolar septa.[4][2]

Function[edit]

They function as a means of collateral ventilation; that is, if the lung is partially deflated, ventilation can occur to some extent through these pores. They equalize the pressure in adjacent alveoli and thus play important role in prevention of collapse of lung.[5] The pores also allow the passage of other materials such as fluid and bacteria, which is an important mechanism of spread of infection in Lobar pneumonia and spread of fibrin in grey hepatisation phase of recovery from the same.

References[edit]

  1. ^ Desplechain C, Foliguet B, Barrat E, Grignon G, Touati F (1983). "[The pores of Kohn in pulmonary alveoli].". Bull Eur Physiopathol Respir 19 (1): 59–68. PMID 6850150. 
  2. ^ a b Miller, J.E. Cotes, D.J. Chinn, M.R. (2006). Lung function : theory and measurement in health and disease (6th ed. ed.). Malden, Mass.: Blackwell Pub. p. 27. ISBN 978-0-632-06493-9. 
  3. ^ H.N. Kohn: “Zur Histologie der indurierenden fibrinösen Pneumonie”. Münchener Medicinische Wochenschrift 1893 40: 42-45
  4. ^ Paediatric pulmonary function testing : 41 tables ([Online-Ausg.] ed.). Basel [u.a.]: Karger. 2005. p. 6. ISBN 3-8055-7753-2. 
  5. ^ Clinical Procedures In Emergency Medicine & Color Atlas Of Emergency Department Procedures. W B Saunders Co. 2005. p. 149. ISBN 1416022503.