It was built between 1674 and 1684 on land belonging to Henry William Portman. It included residences of Alexander Hamilton, 10th Duke of Hamilton, Sir Brook Bridges, 3rd Baronet, Henry Pelham-Clinton, 4th Duke of Newcastle-under-Lyne, George Keppel, 6th Earl of Albemarle, Sir Charles Asgill, 1st Baronet and William Henry Percy.
 Notable houses
- No. 20 – Home House, built by Robert Adam between 1773 and 1777 for Elizabeth, Countess of Home, and later used by the Courtauld Institute.
- No. 22 – Montagu House, built in the northwest corner of the square by James Stuart between 1777 and 1781 for Mrs. Elizabeth Montagu, demolished in the Blitz by an incendiary bomb.
- No. 30 – Churchill Hotel, incorporating the Michelin-starred Locanda Locatelli
 See also
No's 11-15 built in 1773-1776 by the famous architect James Wyatt in cooperation with his brother the builder Samuel Wyatt. First houses in which Coade stone was used. Demolished in the 20th century. Ref: James Wyatt, architect to George III. Author John Martin Robinson. Yale University Press 2012
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