Posizolid

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Posizolid
Posizolid.png
Systematic (IUPAC) name
(5R)-3-[4-[1-[(2S)-2,3-Dihydroxypropanoyl]-3,6-dihydro-2H-pyridin-4-yl]-3,5-difluorophenyl]-5-(1,2-oxazol-3-yloxymethyl)-1,3-oxazolidin-2-one
Clinical data
Legal status
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Identifiers
CAS number 252260-02-9
ATC code None
PubChem CID 213049
UNII 82V2M8K24R YesY
Synonyms AZD2563
Chemical data
Formula C21H21F2N3O7 
Mol. mass 465.40 g/mol
 YesY (what is this?)  (verify)

Posizolid is an oxazolidinone antibiotic under investigation by AstraZeneca for the treatment of bacterial infections. At a concentration of 2 mg/L it inhibited 98% of all Gram-positive bacteria tested in vitro.[1]

References[edit]

  1. ^ Wookey, A.; Turner, P. J.; Greenhalgh, J. M.; Eastwood, M.; Clarke, J.; Sefton, C. (2004). "AZD2563, a novel oxazolidinone: definition of antibacterial spectrum, assessment of bactericidal potential and the impact of miscellaneous factors on activity in vitro". Clinical Microbiology and Infection 10 (3): 247–254. doi:10.1111/j.1198-743X.2004.00770.x. PMID 15008947.